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Programme
EUROPEAN STATISTICAL FORUM
November
19th
2012 - Hotel Palace – Berlin
SCIENTIFIC BOARD:
Lisa Comarella
Senior Statistician and Head of Methodologial Biostatistis Unit,
Cros NT Group
Frank Fleischer
Global BCA, Boehringer Ingelheim Pharma GmbH & Co.
KG
Giacomo Mordenti
Senior Expert Biostatistician, Merk Serono S.A.
AGENDA
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08:30 - 09:00
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Registration
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09:00 - 09:10 |
Welcome |
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09:10 -
09:50 |
Enrichment
designs: a class of adaptive design for identification
of subpopulations of patients in confirmatory trials.
Andy Grieve, Professor Andy Grieve Senior Vice President,
Aptiv Solutions
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09:50 - 10:30 |
An assessment of methods for adaptive patient
selection based on a predictive biomarker.
read
abstract >
Meinhard Kieser, Director of Institute of Medical
Biometry and Informatics, University of Heidelberg
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10:30 - 11:00 |
Coffee Break.
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11:00 - 11:40 |
Stopping one of two sister trials early
for futility – subgroup selection.
read abstract
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Birgit Gaschler-Markefski, Head of Clinical Biostatistics
Germany (Oncology), Patricia Glomb, Senior Statistician,
Clinical, Boehringer Ingelheim Pharma GmbH & Co. KG
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11:40 - 12:20 |
Design and analysis of clinical trials when
treatment benefit is suspected to be different in subpopulations.
read abstract
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Ekkehard Glimm, IIS Statistical Methodology, Novartis Pharma AG
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12:20 - 13:20 |
Lunch
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13:20 - 13:25 |
Activities
renewal
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13:25 - 14:25 |
TUTORIAL: Emerging
methods in benefit-risk assessment and decision-making for
medicinal products
read abstract
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Shahrul Mt-Isa, Statistician, Imperial College, UK
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14:25 - 14:35 |
Discussion
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14:35 - 15:15 |
Adaptive
Subgroup Analysis in clinical trials.
read abstract
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Alexandra Graf, Section of Medical Statistics,
Medical University of Vienna
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15:15 - 15:40 |
Coffee Break
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15:40 - 16:20 |
Impact
of misclassification in genomic enrichment designs.
read abstract >>
Stefano Vezzoli,
Biostatistician, CROS NT
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16:20 - 16:50 |
Panel
discussion
How can adaptive designs be
promoted within a company ?; Which the most important
steps for performing adaptive designs in practice?
With the participation of Ekkehard Glimm, Andy Grieve
and the scientific board |
16:50 -
17.00 |
Conclusion |
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